Kenneth R. HARRAP: search on Z-Library

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1

The 5-HT3antagonist, BRL 43694, does not compromise the efficacy of cisplatin in tumour-bearing mice

Phyllis M. Goddard, Mervyn Jones, Linda A. Pollard, Melanie R. Valenti, Kenneth R. Harrap

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 244 KB

english, 1990

2

Quinazoline antifolates inhibiting thymidylate synthase. Variation of the amino acid

Jones, Terence R., Smithers, Michael J., Betteridge, Richard F., Taylor, Michael A., Jackman, Ann L., Calvert, A. Hilary, Davies, Lawrence C., Harrap, Kenneth R.

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 692 KB

english, 1986

3

TomudexTM(ZD1694): from concept to care, a programme in rational drug discovery

Ann L. Jackman, Kenneth R. Harrap, F. Thomas Boyle

Journal:

Investigational New Drugs

Year:

1996

Language:

english

File:

PDF, 1019 KB

english, 1996

4

The Integrity of Nuclear Proteins Following Incubation of Isolated Nuclei in vitro

Susan M. SELLWOOD, Pamela G. RICHES, Kenneth R. HARRAP, David RICKWOOD, Alexander J. MacGILLIVRAY, Marilyn CAPPS

Journal:

Year:

1975

Language:

english

File:

PDF, 518 KB

english, 1975

5

Genomic Imbalances Associated with Acquired Resistance to Platinum Analogues

Brian Leyland-Jones, Lloyd R. Kelland, Kenneth R. Harrap, Lynne R. Hiorns

Journal:

The American Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 620 KB

english, 1999

6

The effect of diethyldithiocarbamate on the haematological toxicity and antitumour activity of carboplatin

Dible, Sarah E., Siddik, Zahid H., Boxall, Frances E., Harrap, Kenneth R.

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1987

Language:

english

File:

PDF, 656 KB

english, 1987

7

Synthesis and antiviral activity of some new S-adenosyl-L-homocysteine derivatives

Serafinowski, Pawel, Dorland, Erwin, Harrap, Kenneth R., Balzarini, Jan, De Clercq, Erik

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 913 KB

english, 1992

8

Quantitative high-performance liquid chromatography of nucleosides and bases in human plasma

Gordon A. Taylor, Peter J. Dady, Kenneth R. Harrap

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1980

Language:

english

File:

PDF, 843 KB

english, 1980

9

The effects of chlorambucil on the utilization of exogenous thymidine by tumour cells

Pamela G. Riches, Ernest W. Gascoigne, Cecil L. Leese, Kenneth R. Harrap

Journal:

Biochemical Pharmacology

Year:

1975

Language:

english

File:

PDF, 337 KB

english, 1975

10

The comparative tissues distribution of platinum and14C in mice receiving14C-labelled carboplatin

Sarah E. Dible, Zahid H. Siddik, Kenneth R. Harrap

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1988

Language:

english

File:

PDF, 570 KB

english, 1988

11

cis-Diamminedichloroplatinum(II)-induced cell death through apoptosis in sensitive and resistant human ovarian carcinoma cell lines

Michael G. Ormerod, Ciaran O’Neill, David Robertson, Lloyd R. Kelland, Kenneth R. Harrap

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 3.18 MB

english, 1996

12

The clinical pharmacology of the adenosine deaminase inhibitor 2′-deoxycoformycin

John F. Smyth, Rosanne M. Paine, Ann L. Jackman, Kenneth R. Harrap, Marvin M. Chassin, Richard H. Adamson, David G. Johns

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1980

Language:

english

File:

PDF, 798 KB

english, 1980

13

Dinucleotide analogs as inhibitors of thymidine kinase, thymidylate kinase and ribonucleotide reductase

Davies, Lawrence C., Stock, John A., Barrie, S. Elaine, Orr, Rosanne M., Harrap, Kenneth R.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 591 KB

english, 1988

14

The comparative pharmacokinetics of carboplatin and cisplatin in mice and rats

Zahid H. Siddik, David R. Newell, Frances E. Boxall, Kenneth R. Harrap

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 941 KB

english, 1987

15

Preclinical toxicology and tissue platinum distribution of novel oral antitumour platinum complexes: ammine/amine platinum(IV) dicarboxylates

McKeage, Mark J., Morgan, Sarah E., Boxall, Francis E., Murrer, Barry A., Hard, Gordon C., Harrap, Kenneth R.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1994

Language:

english

File:

PDF, 751 KB

english, 1994

16

Human ovarian-carcinoma cell lines and companion xenografts: a disease-oriented approach to new platinum anticancer drug discovery

Lloyd R. Kelland, Mervyn Jones, George Abel, Melanie Valenti, Jean Gwynne, Kenneth R. Harrap

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1992

Language:

english

File:

PDF, 832 KB

english, 1992

17

Comparative distribution and excretion of carboplatin and cisplatin in mice

Zahid H. Siddik, Mervyn Jones, Frances E. Boxall, Kenneth R. Harrap

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1988

Language:

english

File:

PDF, 524 KB

english, 1988

18

The effect of the nucleoside transport inhibitor dipyridamole on the incorporation of [3H]thymidine in the rat

David R. Newell, Patrick M. O'Connor, A. Hilary Calvert, Kenneth R. Harrap

Journal:

Biochemical Pharmacology

Year:

1986

Language:

english

File:

PDF, 619 KB

english, 1986

19

Modulation of anti-metabolite effects: Effects of thymidine on the efficacy of the quinazoline-based thymidylate synthetase inhibitor, cb3717

Ann L. Jackman, Gordon A. Taylor, A.Hilary Calvert, Kenneth R. Harrap

Journal:

Biochemical Pharmacology

Year:

1984

Language:

english

File:

PDF, 779 KB

english, 1984

20

Quinazoline antifolates inhibiting thymidylate synthase: benzoyl ring modifications

Jones, Terence R., Smithers, Michael J., Taylor, Michael A., Jackman, Ann L., Calvert, A. Hilary, Harland, Stephen J., Harrap, Kenneth R.

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 588 KB

english, 1986

21

A reappraisal of the effect upon thymidine kinase of thymidine derivatives carrying large groups at the 5'-position

Barrie, S. Elaine, Davies, Lawrence C., Stock, John A., Harrap, Kenneth R.

Journal:

Journal of Medicinal Chemistry

Year:

1984

Language:

english

File:

PDF, 608 KB

english, 1984

22

IN VIVO INHIBITION OF MOUSE LIVER METHYLTRANSFERASE (MT) ENZYMES FOLLOWING TREATMENT WITH 2'DEOXYCOFORMYCIN (dCf) AND 2'DEOXYADENOSINE (AdR): 171

Renshaw, Jane, Harrap, Kenneth R

Journal:

Pediatric Research

Year:

1985

Language:

english

File:

PDF, 161 KB

english, 1985

23

Die Trennung Von Riboflavin-Derivaten Durch Gegenstromverteilung

Franz Bergel, Robert Cecil Bray, Kenneth Reginald Harrap

Journal:

European Journal of Organic Chemistry

Year:

1957

Language:

german

File:

PDF, 329 KB

german, 1957

24

Inhibition of human leukaemic thymidylate kinase and L1210 ribonucleotide reductase by dinucleotides of adenosine and thymidine and their phosphonate analogues

Rosanne M. Orr, Lawrence C. Davies, John A. Stock, Gordon A. Taylor, Raymond L. Powles, Kenneth R. Harrap

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 610 KB

english, 1988

25

The Binding of [ 3 H]Chlorambucil to Isolated Nuclear Proteins of the Yoshida Ascites Sarcoma

SELLWOOD, SUSAN M., RICHES, PAMELA G., HARRAP, KENNETH R.

Journal:

Biochemical Society Transactions

Year:

1975

Language:

english

File:

PDF, 175 KB

english, 1975

26

Anti-Folate Toxicity and its Reversal

HARRAP, KENNETH R.

Journal:

Biochemical Society Transactions

Year:

1976

Language:

english

File:

PDF, 332 KB

english, 1976

27

The clinical pharmacokinetics of the novel antifolate N10-propargyl-5,8-dideazafolic acid (CB 3717)

Dawn L. Alison, David R. Newell, Christiana Sessa, Stephen J. Harland, Leigh I. Hart, Kenneth R. Harrap, A. Hilary Calvert

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1985

Language:

english

File:

PDF, 614 KB

english, 1985

28

Estimation of chlorambucil, phenyl acetic mustard and prednimustine in human plasma by high-performance liquid chromatography

David R. Newell, Leigh I. Hart, Kenneth R. Harrap

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1979

Language:

english

File:

PDF, 383 KB

english, 1979

29

Some effects of chlorambucil on the uptake and utilization of sulphydryl-containing compounds by tumour cells

Kenneth R. Harrap, Pamela G. Riches, Robert C. Jackson, Carol A. Smith

Journal:

Biochemical Pharmacology

Year:

1973

Language:

english

File:

PDF, 535 KB

english, 1973

30

Phosphorylation of Nuclear Proteins in Rodent Tissues

RICHES, PAMELA G., HARRAP, KENNETH R., SELLWOOD, SUSAN M., RICKWOOD, DAVID, MacGILLIVRAY, ALEXANDER J.

Journal:

Biochemical Society Transactions

Year:

1973

Language:

english

File:

PDF, 211 KB

english, 1973

31

Cisplatin || ANTITUMOR, TOXIC AND BIOCHEMICAL PROPERTIES OF CISPLATIN AND EIGHT OTHER PLATINUM COMPLEXES

Harrap, Kenneth R.

Year:

1980

Language:

english

File:

PDF, 1.13 MB

english, 1980

32

Deoxyribonucleoside triphosphate pools and adenosine toxicity

John F. Smyth, Kenneth R. Harrap

Journal:

Biochemical Pharmacology

Year:

1977

Language:

english

File:

PDF, 398 KB

english, 1977

33

Selectivity of action of alkylating agents and drug resistance. 4. Synthesis of tritium-labeled chlorambucil and a study of its cellular uptake by drug-sensitive and drug-resistant strains of the Yoshida ascites sarcoma in vitro

Hill, Bridget T., Jarman, Michael, Harrap, Kenneth R.

Journal:

Journal of Medicinal Chemistry

Year:

1971

Language:

english

File:

PDF, 667 KB

english, 1971

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